Health & Medical Public Health

Prevalence and Complications of Diabetes Mellitus in Northern Africa

Prevalence and Complications of Diabetes Mellitus in Northern Africa

Methods

Search Strategy for Identification of Studies


We conducted a systematic review of all papers published on diabetes in adults in North Africa between January 1990 to July 2012 and available in PUBMED database. North Africa in this article is defined as the UN sub region and includes Morocco, Algeria, Tunisia, Libya, Egypt, Sudan, South Sudan and Western Sahara. Studies were included if they were based on adults aged ≥18 years, were carried out in the UN sub region of North Africa, assessed prevalence of diabetes and related microvascular complications, and if the sample size was ≥50 participants. The search was limited to studies done in humans and no language restrictions were used.

Search Strategy for Identification of Studies on Prevalence of Diabetes


Combined keyword search on PUBMED identified 1037 articles of which 962 were excluded because studies were conducted outside the region of interest, described diabetes pathogenesis, included genetic or microbiological research, reviewed another disease, used data based on the analysis of patients records, or were case reports (see Additional file 1 for a description of the review and Additional file 2 for the flow-chart). Of the remaining seventy-four articles after removal of duplicates, twenty-one papers were reviewed for prevalence of diabetes. Two papers were manually included after examining the references of included articles. In total, twelve studies met the inclusion criteria and were included for data on prevalence of type 2 diabetes in North Africa.

Search Strategy for Identification of Studies on Diabetes Complications


Fifty-three papers were reviewed for data on microvascular (retinopathy, nephrology, neuropathy and micoalbuminuria) diabetes complications of which forty-six were excluded because they were based on management and screening options, and conditions such as periodontal problems, mental health problems, or their sample size was too small (i.e. n<50). Two studies were manually included after examining the references of included articles. In total, nine articles met the inclusion criteria and were included for data on microvascular diabetic complications.



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